-A A +A
Silicon has been widely used as a material for microelectronic for more than 60 years, attracting considerable scientific interest as a promising tool for the manufacture of implantable medical devices in the context of neurodegenerative diseases. However, the use of such material involves responsibilities due to its toxicity, and researchers are pushing towards the generation of new classes of composite semiconductors, including the Silicon Carbide (3C-SiC). In the present work, we tested the biocompatibility of Silicon and 3C-SiC using an in vitro model of human neuronal stem cells derived from dental pulp (DP-NSCs) and mouse Olfactory Ensheathing Cells (OECs), a particular glial cell type showing stem cell characteristics. Specifically, we investigated the effects of 3C-SiC on neural cell morphology, viability and mitochondrial membrane potential. Data showed that both DP-NSCs and OECs, cultured on 3C-SiC …
Nature Publishing Group
Publication date: 
8 Aug 2019

Gabriele Bonaventura, Rosario Iemmolo, Valentina La Cognata, Massimo Zimbone, Francesco La Via, Maria Elena Fragalà, Maria Luisa Barcellona, Rosalia Pellitteri, Sebastiano Cavallaro

Biblio References: 
Volume: 9 Issue: 1 Pages: 1-13
Scientific reports